Prescription, Pharmacy & Cancer Drugs » Prescription Drugs 12 » Pantoprazole Generic Protonix
Indications1. For the symptomatic improvement and healing of gastrointestinal diseases which require a reduction in acid secretion: -Duodenal ulcer -Gastric ulcer -Gastro-oesophageal reflux disease (GORD) *For the treatment of mild reflux disease and associated symptoms (e.g. heartburn acid regurgitation pain on swallowing) *Reflux oesophagitis -Zollinger-Ellison Syndrome 2. Eradication of Helicobacter pylori (hereinafter referred to as H. pylori) in combination with -clarithromycin and amoxycillin or -clarithromycin and metronidazole or -amoxycillin and metronidazole(see Dosage and Administration) in cases of duodenal ulcer and gastric ulcer with the objective of reducing the recurrence of duodenal and gastric ulcers caused by this microorganism. The NIH have recommended that regimens to eradicate H. pylori in patients with PUD should contain both anti-secretory agents and anti-microbial agents (to which H. pylori has been demonstrated to be sensitive in vivo). A trial by Bardhan in patients with gastritis florid duodenal ulcer or history of duodenal ulcer has demonstrated that pantoprazole 40 mg twice daily in the combination with tinidazole 500 mg twice daily and clarithromycin 250 mg twice daily for 10 days is effective in eradicating H. pylori in 86% of cases. Following combination therapy the DU healing rate was 100% after 1 month. 3. Prevention of gastroduodenal ulcers induced by non-selective non-steroidal anti-inflammatory drugs (NSAIDs) in patients at risk with a need for continuous NSAID treatment. Maintenance:Pantoprazole tablets are indicated for maintenance treatment of reflux oesophagitis duodenal ulcer gastric ulcer and Zollinger-Ellison syndrome. Prolonged treatment should be considered:-in patients who have recurrent peptic ulceration where the pathogenesis of the ulcer is not related to H. pylori infection; or -where repeated eradication therapy is unsuccessful; or who have a past history of perforation or bleeding from an ulcer. Dosage and AdministrationDuodenal UlcerThe recommended oral dosage is one gastro-resistant 40 mg pantoprazole tablet per day. A duodenal ulcer generally heals within 2 weeks. If a 2-week period of treatment is not sufficient healing will be achieved in almost all cases within a further 2 weeks.Gastric UlcerThe recommended oral dosage is one gastro-resistant 40 mg pantoprazole tablet per day.A 4-week period is usually required for the treatment of gastric ulcers. If this is not sufficient healing will usually be achieved within a further 4 weeks.GORDFor mild reflux disease and the associated symptoms the recommended dosage is one pantoprazole 20 mg tablet per day. Symptom relief is generally accomplished within 2-4 weeks. If symptom control has not been achieved after four weeks treatment with pantoprazole 20 mg tablets daily further investigation is recommended.For treatment of reflux oesophagitis the recommended oral dosage is one pantoprazole 40 mg tablet per day. A 4-week period is usually required for treatment of reflux oesophagitis however if this is not sufficient healing will usually be achieved within a further 4 weeks.Zollinger-Ellison SyndromeThe recommended oral dosage is one gastro-resistant pantoprazole tablet 40 mg per day.Prevention of gastroduodenal ulcers induced by non-selective non-steroidal anti-inflammatory drugs (NSAIDs) in patients at risk with a need for continuous NSAID treatment.The recommended oral dosage is one gastro-resistant pantoprazole tablet 20 mg per day.MaintenanceDuodenal and Gastric Ulcer and Zollinger-Ellison Syndrome:For long-term management a maintenance dose of one gastro-resistant pantoprazole tablet 40 mg per day is recommended.Reflux OesophagitisA maintenance dose of one pantoprazole tablet 20 mg per day is recommended increasing to 40 mg per day if relapse occurs. After healing of the relapse the dosage can be reduced again to 20 mg.Experience with long-term administration in man over several years is available in a limited number of patients. Therefore long-term treatment exceeding 1 year may be considered after careful evaluation of the risk benefit ratio. Patients should then be kept under regular surveillance.Use in childrenThere are no data currently available on the use of pantoprazole in children.Use in the elderlyThe daily dose of 20 mg or 40 mg can be given. An exception is combination therapy for eradication of H. pylori where also elderly patients should receive the usual pantoprazole dose (2 x 40 mg/day) during 1-week treatment.Impaired Renal FunctionThe daily dose of 20 mg or 40 mg can be given.Impaired Liver FunctionIn patients with severe liver impairment the dose has to be reduced to 20 mg pantoprazole per day.
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Arimidex (Anastrozole) Arimidex (Anastrozole) blocks the use of estrogen by certain types of breast cancer that require estrogen to grow. Buy Arimidex (Anastrozole) and other Cancer products online at Medstore. About Arimidex (Anastrozole): Product Type: Cancer Brand name: Arimidex Generic name: Anastrozole What is the most important information I should know about arimidex? Before taking arimidex tell your doctor if you have any other medical conditions or if you take other medications. You may not be able to take arimidex or you may require a dosage adjustment or special monitoring during treatment. What is arimidex? Arimidex blocks the use of estrogen by certain types of breast cancer that require estrogen to grow. Arimidex is used to treat breast cancer. Arimidex may also be used for purposes other than those listed in this medication guide. Who should not take arimidex? Before taking arimidex tell your doctor if you have any other medical conditions or if you take other medications. You may not be able to take arimidex or you may require a dosage adjustment or special monitoring during treatment. Arimidex is in the FDA pregnancy category D. This means that arimidex is known to harm an unborn baby. Do not take arimidex if you are pregnant. It is not known whether arimidex passes into breast milk. Do not take arimidex if you are breast-feeding a baby. How should I take arimidex? Take arimidex exactly as directed by your doctor. If you do not understand these directions ask your pharmacist nurse or doctor to explain them to you. Take each dose with a full glass (8 ounces) of water. Arimidex is usually taken once a day. Follow your doctor's instructions. Arimidex can be taken with or without food. Store arimidex at room temperature away from moisture and heat. What happens if I miss a dose? Take the missed dose as soon as you remember. However if it is almost time for your next dose skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication unless your doctor directs otherwise. What happens if I overdose? An overdose of arimidex is unlikely to threaten life. Call an emergency room or a poison control center for advice if you suspect that a very large dose of arimidex has been ingested. What should I avoid while taking arimidex? There are no restrictions on food beverages or activities while taking arimidex unless otherwise directed by your doctor. What are the possible side effects of arimidex? Stop taking arimidex and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips tongue or face; or hives) to arimidex. Other less serious side effects may be more likely to occur. Continue to take arimidex and talk to your doctor if you experience • diarrhea; • nausea or vomiting; • constipation; • weakness; • muscle or bone pain; • headache; • hot flashes; • shortness of breath or coughing; • dizziness; • swelling or water retention; • loss of appetite; • vaginal dryness; • weight gain; or • rash. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect arimidex? There are no known interactions between arimidex and other medications. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines during treatment with arimidex. Generic Arimidex (Anastrozole) Altraz Anastrole 1mg 10 tabs 1mg 20 tabs 1mg 40 tabs 1mg 30 tabs 1mg 50 tabs Anastrozole Arimidex


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